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Cameras catch the highs and lows over the course of a year as nine dangerously overweight individuals try to shed the pounds before it's too late....

Jack, 25, weighs in at 29 stone and could be the poster boy for today's obesity epidemic. With Jessie and the team's help though, Jack is determined...

Liz's weight problems have spiralled out of control, and she currently stands at 34 stone. Can Jessie and the team help the 38-year-old conquer her...

Jessie and the team come to the aid of 32-year-old Claire, who weighs 26-and-a-half stone. Things haven't been simple for Claire, and her food issues...

A&E nurse Bev, 51, has tried everything to lose weight, from diets to surgery, but nothing has worked. Now 27-and-a-half stone, Bev turns to...

The prognosis isn't looking good for Sandy. He weighs 34 stone and, unless action is taken, an early death awaits. Can Jessie and co help Sandy get...

Twenty-nine-year-old Lee is an inspiration for bigger people and is determined to lose weight. Can Jessie and the team help him end his unrestrained...

Stepping off the scales, the powerful documentary series reaches its conclusion. Find out if Jessie and the team can work their magic one last time...

Five best friends start a challenge to lose 50 pounds each in 120 days to compete in a triathlon.

In this unique experiment, nine 21st century volunteers subject themselves to the weight loss diets and fitness regimes of previous generations. But...

The Biggest Loser features obese people competing to win a cash prize by losing the highest percentage of weight relative to their initial weight.

Explore how the late Gwen Shamblin Lara, who founded the controversial Remnant Fellowship Church and created the Christian weight loss program The...

Geneticist Giles Yeo and his team assess five overweight volunteers, before putting them on personalised diets tailored to their bodies and brains.